Methotrexate free chemotherapy and limb salvage surgery for paediatric osteosarcoma in India
نویسندگان
چکیده
منابع مشابه
Study on the efficacy of neoadjuvant chemotherapy on limb salvage surgery for osteosarcoma
In this study, 32 osteosarcoma patients admitted in the department of orthopedics from 2008 to 2016 were selected as subjects. Percutaneous intra-arterial chemotherapy was performed on 17 patients on the day before admission, and then the general chemotherapy was carried out on next day. After limb salvage surgery, the previous chemotherapy was repeated for 4 times. Before limb salvage surgery,...
متن کاملNeoadjuvant chemotherapy combined with limb salvage surgery in patients with limb osteosarcoma of Enneking stage II: a retrospective study
OBJECTIVE To explore the effect of neoadjuvant chemotherapy combined with limb salvage surgery in patients with limb osteosarcoma of Enneking stage II. PATIENTS AND METHODS Medical records of 98 patients who met the inclusion criteria were retrospectively analyzed. Of these patients, 56 cases who received neoadjuvant chemotherapy combined with limb salvage surgery were listed as group A, whil...
متن کاملOsteosarcoma of the limb. Amputation or limb salvage in patients treated by neoadjuvant chemotherapy.
THE JOURNAL OF BONE AND JOINT SURGERY G. Bacci, MD S. Ferrari, MD A. Longhi, MD C. Forni, RN M. Versari, MA Department of Chemotherapy S. Lari, MD Department of Anaesthesia M. Mercuri, MD D. Donati, MD 5th Ward of Orthopaedic Surgery F. Bertoni, MD Service of Anatomy and Pathology E. Pignotti, MA Service of Statistics of the Department of Musculoskeletal Oncology Rizzoli Orthopaedic Institute, ...
متن کاملAdvances in limb salvage treatment of osteosarcoma
Osteosarcoma is the most common primary malignant bone tumor; its standard treatment includes neoadjuvant chemotherapy combined with surgery. Neoadjuvant chemotherapy has significantly improved the 5-year survival and limb salvage rates in osteosarcoma since the 1870s. The survival rate of patients with limb salvage was not inferior to that of amputees, and therefore, limb salvage has become th...
متن کاملRisk factors for local recurrences after limb-salvage surgery for high-grade osteosarcoma of the extremities.
BACKGROUND Improvements in preoperative staging as well as in chemotherapeutic regimens have made limb-salvage surgery a reliable modality of treatment for high-grade osteosarcomas of the extremities, with local recurrences in most series of less than 10% after this type of surgery. The quality of surgical margins and local response to preoperative chemotherapy are known to be the most signific...
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ژورنال
عنوان ژورنال: Indian Journal of Orthopaedics
سال: 2018
ISSN: 0019-5413
DOI: 10.4103/ortho.ijortho_195_17